Hydroxypropyl methylcellulose (HPMC) chinhu chakakosha chine huwandu hwakawanda hwekushandisa muindasitiri yemishonga pamwe nemamwe maindasitiri akadai sechikafu, zvekuzora uye kuvaka. Iko kudiwa kweHPMC kwave kukura zvakadzikama nekufamba kwemakore nekuda kwezvimiro zvayo zvakasiyana sekukora, kusunga, kugadzira firimu uye kuchengetedza mvura. Muchikamu chino, tichakurukura nzira yekugadzira alkaline leaching yehydroxypropyl methylcellulose (HPMC).
Iyo alkali leaching yekugadzira nzira yehydroxypropyl methylcellulose (HPMC) inzira iyo cellulose inopindirana nepropylene oxide uye methyl chloride pamberi pealkali. Maitiro acho anoitika pasi petembiricha, kumanikidzwa uye nguva inodzorwa mamiriro ekuburitsa emhando yepamusoro HPMC zvigadzirwa.
Nhanho yekutanga mukugadzira HPMC uchishandisa alkaline leaching yekugadzira nzira ndeye kugadzirira cellulose mbishi zvinhu. Cellulose inotanga kucheneswa nekubvisa chero tsvina yozoshandurwa kuita alkali cellulose nekurapwa nealkali senge sodium hydroxide. Iyi nhanho yakakosha nekuti inowedzera reactivity ye cellulose nema reagents anoshandiswa mumatanho anotevera.
Alkali cellulose inobatwa nemusanganiswa wepropylene oxide uye methyl chloride pasi petembiricha inodzorwa uye kumanikidzwa. Kuita pakati pealkali cellulose uye reagent inoguma mukuumbwa kwechigadzirwa, chinova musanganiswa wehydroxypropyl methylcellulose uye zvimwe zvakabuda.
Iko kusanganiswa kunoshambidzwa, kusagadziriswa uye kusefa kuti ibvise tsvina yakadai semareagents asina kugadziriswa uye ne-zvigadzirwa. Iyo inoguma mhinduro inobva yaiswa ne evaporation kuti uwane yakanyanya kuchena HPMC chigadzirwa.
Iyo alkali leaching yekugadzira nzira yehydroxypropyl methylcellulose (HPMC) ine zvakawanda zvakanaka zvichienzaniswa nedzimwe nzira dzekugadzira senge etherification. Chimwe chezvakanakira ndechekuti inzira inoshamwaridzana nenharaunda. Kusiyana nemamwe maitiro, iyo alkali leaching yekugadzira nzira haishandise halogenated solvents inokuvadza nharaunda uye hutano hwevanhu.
Imwe mukana weiyi nzira kugadzirwa kwepamusoro-kuchena HPMC zvigadzirwa. Inodzorwa maitiro ekuita inovimbisa kuti chigadzirwa chekupedzisira chiri chemhando inowirirana uye chakakodzera kune akasiyana maapplication.
Kushandiswa kweHPMC muindasitiri yemishonga kwakakosha pakugadzirwa kwemapiritsi, macapsules uye mamwe mafomu emushonga. HPMC inogona kushandiswa sebhainda, disintegrant, coating agent, etc. Kushandiswa kweHPMC mune izvi zvikumbiro kunovimbisa kuti fomu redosi nderemhando yepamusoro uye rinosangana nezvinodiwa.
HPMC inoshandiswa zvakare seyakakora, emulsifier uye stabilizer muindasitiri yechikafu. Iko kushandiswa kweHPMC mune zvigadzirwa zvechikafu kunovimbisa kuenderana mameseji, viscosity uye mhando.
Muindasitiri yekuvaka, HPMC inoshandiswa sesemende yekuwedzera kusimudzira kushanda, kuchengetedza mvura uye kubatanidza zvivakwa zvesimende. Iko kushandiswa kweHPMC kunovimbisa kuti zvigadzirwa zvekuvaka ndezvemhando yepamusoro uye zvinoenderana nezvinodiwa.
Muchidimbu, iyo alkali leaching yekugadzira nzira yehydroxypropyl methylcellulose (HPMC) inzira yekugadzira yepamusoro-mhando zvigadzirwa zveHPMC uye inoshandiswa zvakanyanya mumaindasitiri akasiyana semishonga, chikafu, uye kuvaka. Iko kushandiswa kweHPMC mune izvi zvikumbiro kunovimbisa kuti chigadzirwa chemhando yepamusoro uye chinosangana nezvinodiwa. Iyi nzira yekugadzira zvakare ine hushamwari kwezvakatipoteredza uye inogadzira yakakwirira-kuchena HPMC chigadzirwa.
Nguva yekutumira: Sep-15-2023