Hydroxypropyl methylcellulose (HPMC) uye hypromellose zvechokwadi musanganiswa mumwe chete, uye mazwi anowanzo shandiswa zvakasiyana. Aya mazita akaomarara emhando dzakajairwa dzema cellulose-based polymers ane huwandu hwakasiyana hwekushandisa mumaindasitiri akasiyana anosanganisira emishonga, chikafu uye zvekuzora.
1.Chemical chimiro uye kuumbwa:
Hydroxypropylmethylcellulose (HPMC) igadziriso yekugadzira cellulose, yakasikwa polymer inowanikwa muchirimwa sero madziro. Iyo kemikari chimiro cheHPMC inowanikwa nekuunza hydroxypropyl uye methyl mapoka pahwaro hweselulosi. Iro hydroxypropyl boka rinoita kuti cellulose iwedzere kunyungudika mumvura, uye boka remethyl rinowedzera kugadzikana uye rinoderedza reactivity yayo.
2. Maitiro ekugadzira:
Kugadzirwa kwehydroxypropyl methylcellulose kunosanganisira kurapa cellulose nepropylene oxide kuunza hydroxypropyl mapoka uyezve nemethyl chloride kuwedzera methyl mapoka. Iyo dhigirii yekutsiva (DS) yehydroxypropyl uye methyl inogona kugadziridzwa panguva yekugadzira maitiro, zvichikonzera akasiyana mamakisi eHPMC ane akasiyana zvivakwa.
3. Zvimiro zvemuviri:
HPMC ihupfu chena kusvika kushoma-chena, isinganhuhwi uye isinganakidze. Hunhu hwayo hwemuviri, senge viscosity uye solubility, zvinoenderana nehuwandu hwekutsiva uye huremu hwemamorekuru epolymer. Mumamiriro ezvinhu akajairika, inonyungudika nyore nyore mumvura, ichiita sarudzo yakajeka uye isina ruvara.
4. Zvinangwa zvekurapa:
Imwe yemashandisirwo makuru eHPMC iri muindasitiri yemishonga. Inoshandiswa zvakanyanya semushonga wemishonga uye inoita mabasa akasiyana-siyana mukugadzirira kwemishonga. HPMC inowanzowanikwa mumuromo yakasimba dosage mafomu akadai semapiritsi, capsules, uye mapiritsi. Inoshanda sebhainda, disintegrant, uye inodzorwa kuburitsa mumiriri, zvichibatsira mukugadzikana kwese uye bioavailability yemushonga.
5. Basa mukugadzirisa kusunungurwa gadziriro:
Kugona kweHPMC kugadzira majiroji mumishonga ine aqueous inoita kuti ive yakakosha mukudzorwa-kuburitswa kwemishonga maumbirwo. Nekusiyanisa viscosity uye gel-kuumba zvivakwa, vezvemishonga vesainzi vanogona kudzora kuburitswa kweanoshanda zvinongedzo, nekudaro vachiwana inoenderera uye yakareba zvinodhaka chiito.
6. Kushandiswa muindasitiri yezvekudya:
Muindasitiri yechikafu, HPMC inoshandiswa seyakakora, inosimbisa uye emulsifier. Inovandudza magadzirirwo ezvokudya zvakasiyana-siyana, kusanganisira sosi, soups uye zvigadzirwa zvemukaka. Pamusoro pezvo, HPMC inoshandiswa mukubika-gluten-isina kusimudzira chimiro uye kunyorovesa zvinhu zvezvigadzirwa zvisina guten.
7. Kuvaka uye zvekuvaka:
HPMC inoshandiswa muindasitiri yekuvaka muzvigadzirwa zvakaita sematairi anonamira, simende-based plasters uye gypsum-based materials. Inovandudza kugadzirisika, kuchengetwa kwemvura uye kunamatira zvinhu zvezvigadzirwa izvi.
8. Zvizoro uye zvigadzirwa zvekuchengeta munhu:
Hypromellose zvakare chinhu chakajairika muzvizoro uye zvigadzirwa zvekuchengeta munhu. Inoshandiswa mumakirimu, lotions uye shampoos nekuda kwekukora uye kudzikamisa zvinhu. Uyezve, inobatsira kuvandudza kuumbwa kwese uye kunzwa kwechigadzirwa.
9. Firimu coating mumishonga:
HPMC inoshandiswa zvakanyanya muindasitiri yemishonga yekuputira firimu remapiritsi. Mapiritsi akafukidzwa nefirimu anopa chimiro chakagadziridzwa, kuravira masking uye kudzivirira kubva kune zvakatipoteredza zvinhu. Mafirimu eHPMC anopa jira rakatsetseka uye rakafanana, rinovandudza huwandu hwese hwechigadzirwa chemushonga.
13. Mhedziso:
Hydroxypropyl methylcellulose (HPMC) uye hypromellose inoreva imwechete cellulose-based polymer ine akasiyana ekushandisa mumishonga, chikafu, zvekuzora, uye kuvaka. Hunhu hwayo hwakasiyana, hwakadai sekunyungudika, kugadzikana uye biodegradability, zvinobatsira mukushandiswa kwayo kwakapararira. Iko kuita kwakasiyana-siyana kweHPMC mumaindasitiri akasiyana kunoratidza kukosha kwayo sechinhu chakawanda chinoshanda, uye kuenderera mberi.kutsvaga nekusimudzira kunogona kuburitsa mamwe maapplication mune ramangwana.
Iyi ongororo yakazara ine chinangwa chekupa kunzwisiswa kwakadzama kwehydroxypropyl methylcellulose uye hypromellose, kujekesa kukosha kwazvo mundima dzakasiyana, uye kujekesa basa ravo mukugadzira akawanda zvigadzirwa uye magadzirirwo.
Nguva yekutumira: Zvita-21-2023