HPMC (hydroxypropyl methylcellulose) inokora uye inodzikamisa inowanzoshandiswa mukuvaka, machira, mishonga uye chikafu. HPMC 15 cps zvinoreva kuti viscosity yayo i 15 centipoise, inova giredhi yakaderera viscosity.
1. Wedzera HPMC concentration
Iyo yakanyanya kunanga uye inoshanda nzira yekuwedzera viscosity yeHPMC ndeyekuwedzera iyo yekuisa mumhinduro. Kana chikamu chikuru cheHPMC chikawedzera, viscosity yemhinduro inowedzerawo. Nheyo yeiyi nzira ndeyekuti HPMC inowedzera viscosity yemhinduro nekugadzira matatu-dimensional network chimiro. Sezvo nhamba yeHPMC mamorekuru mune mhinduro inowedzera, density uye simba retiweki chimiro zvichawedzerawo, nekudaro kuwedzera viscosity yemhinduro. Zvisinei, pane muganhu wekuwedzera kuisa pfungwa. Kunyanya kuwanda kweHPMC kunokonzeresa kuti fluidity yemhinduro kudzikire, uye inogona kutokanganisa kuita kwayo mumashandisirwo chaiwo, akadai sekuvaka uye kushanda.
2. Dzora kutonhora kwemhinduro
Tembiricha ine simba guru pane solubility uye viscosity yeHPMC. Pakudzika kwekushisa, viscosity yeHPMC mhinduro yakakwirira; nepo pane tembiricha yepamusoro, iyo viscosity yeHPMC mhinduro inoderera. Naizvozvo, kudzikisa tembiricha yemhinduro zvakakodzera panguva yekushandiswa kunogona kuwedzera viscosity yeHPMC. Izvo zvinofanirwa kucherechedzwa kuti solubility yeHPMC mune mhinduro yakasiyana pane dzakasiyana tembiricha. Kazhinji zviri nyore kupararira mumvura inotonhora, asi zvinotora imwe nguva yenguva kuti iparadze zvachose. Inonyungudika nekukurumidza mumvura inodziya, asi viscosity yakaderera.
3. Shandura pH kukosha kwe solvent
Iyo viscosity yeHPMC inonzwawo kune pH kukosha kwemhinduro. Pasi pezvakarerekera kana padhuze-zvakarerekera mamiriro, iyo viscosity yeHPMC mhinduro ndiyo yepamusoro. Kana iyo pH kukosha kwemhinduro ikatsauka kubva mukusarerekera, iyo viscosity inogona kuderera. Naizvozvo, viscosity yeHPMC mhinduro inogona kuwedzerwa nekugadzirisa zvakanaka pH kukosha kwemhinduro (semuenzaniso, nekuwedzera buffer kana acid-base regulator). Nekudaro, mukushanda chaiko, kugadziridzwa kweiyo pH kukosha kunofanirwa kuve nekuchenjerera, nekuti shanduko huru dzinogona kukonzera HPMC kudzikira kana kuderera kwekuita.
4. Sarudza mushonga wakakodzera
Iyo solubility uye viscosity yeHPMC mune akasiyana solvent masisitimu akasiyana. Kunyange zvazvo HPMC inonyanya kushandiswa mukugadzirisa kwemvura, kuwedzerwa kwezvimwe zvinonyungudutsa zvehupenyu (zvakadai se ethanol, isopropanol, nezvimwewo) kana munyu wakasiyana-siyana unogona kushandura chain conformation ye HPMC molecule, nokudaro inokanganisa viscosity. Semuenzaniso, diki diki ye organic solvent inogona kuderedza kupindira kwemamorekuru emvura paHPMC, nekudaro kuwedzera viscosity yemhinduro. Mukushanda chaiko, zvinodikanwa kuti usarudze zvakakodzera organic solvents zvinoenderana nekushandisa chaiko.
5. Shandisa zviyamuro zvekukora
Mune zvimwe zviitiko, zvimwe zviyamuro zvekukora zvinogona kuwedzerwa kuHPMC kuti uwane mhedzisiro yekuwedzera viscosity. Inowanzoshandiswa thickening aids zvinosanganisira xanthan chingamu, guar gum, carbomer, etc. Izvi additives anopindirana HPMC mamorekuru kuumba yakasimba gel kana network chimiro, kuwedzera kuwedzera viscosity mhinduro. Semuenzaniso, xanthan chingamu ndeye yakasikwa polysaccharide ine yakasimba thickening maitiro. Kana yakashandiswa neHPMC, izvo zviviri zvinogona kugadzira synergistic mhedzisiro uye zvakanyanya kuwedzera viscosity yehurongwa.
6. Shandura dhigirii rekutsiva HPMC
Iyo viscosity yeHPMC ine hukama zvakare nedhigirii rekutsiviwa kweayo methoxy uye hydroxypropoxy mapoka. Iyo dhigirii yekutsiva inokanganisa kunyungudika kwayo uye viscosity yemhinduro. Nekusarudza HPMC ine madhigirii akasiyana ekutsiva, iyo viscosity yemhinduro inogona kugadziriswa. Kana yakakwira viscosity HPMC ichidikanwa, chigadzirwa chine methoxy yakakwira yemukati inogona kusarudzwa, nekuti iyo yakakwira methoxy yemukati, yakasimba iyo hydrophobicity yeHPMC, uye viscosity mushure mekunyungudika yakakwira.
7. Wedzera nguva yekuparara
Iyo nguva iyo HPMC inonyungudika ichakanganisawo viscosity yayo. Kana HPMC isati yanyungudika zvachose, viscosity yemhinduro haizosviki kune yakanaka mamiriro. Naizvozvo, zvakakodzera kuwedzera nguva yekuparara kweHPMC mumvura kuti ive nechokwadi chekuti HPMC yakazara hydrated inogona zvinobudirira kuwedzera viscosity yemhinduro yayo. Kunyanya kana ichinyungudika pakudziya kwakadzika, iyo HPMC yekumisa maitiro inogona kunonoka, uye kuwedzera nguva kwakakosha.
8. Shandura mamiriro ekugera
Iyo viscosity yeHPMC zvakare ine hukama neshear simba iyo inoiswa mukati mekushandiswa. Pasi pemamiriro ekumusoro ekugera, viscosity yeHPMC mhinduro ichaderera kwechinguva, asi kana shear yamira, viscosity inopora. Kune maitiro anoda kuwedzera viscosity, simba rekuveura iro mhinduro rinogadziriswa rinogona kuderedzwa, kana rinogona kushandiswa pasi pemamiriro ekucheka kwepamusoro kuchengetedza viscosity yakakwirira.
9. Sarudza kwakakodzera molecular uremu
Iyo molecular huremu hweHPMC inokanganisa zvakananga viscosity yayo. HPMC ine huremu hwakakura hwemamorekuru inoumba yakakura network chimiro mune mhinduro, zvichikonzera kukwirisa viscosity. Kana iwe uchida kuwedzera viscosity yeHPMC, unogona kusarudza zvigadzirwa zveHPMC zvine huremu hwepamusoro. Kunyangwe HPMC 15 cps iri yakaderera-viscosity chigadzirwa, iyo viscosity inogona kuwedzerwa nekusarudza yakakwirira-mamorekuru-huremu musiyano wechigadzirwa chimwe chete.
10. Funga nezvezvakatipoteredza
Zvakatipoteredza zvinhu zvakaita sehunyoro uye kudzvanywa zvinogona zvakare kuve nekumwe kukanganisa pane viscosity yeHPMC mhinduro. Munzvimbo ine hunyoro hwepamusoro, HPMC inogona kutora hunyoro kubva kumhepo, zvichiita kuti viscosity yayo iderere. Kuti udzivise izvi, mamiriro ezvakatipoteredza ekugadzira kana kushandisa saiti anogona kudzorwa zvakanaka kuchengetedza nharaunda yakaoma uye pakumanikidzwa kwakakodzera kuchengetedza viscosity yeHPMC mhinduro.
Pane nzira dzakawanda dzekuwedzera viscosity yeHPMC 15 cps mhinduro, kusanganisira kuwedzera kuomesa, kudzora tembiricha, kugadzirisa pH, kushandisa thickening aids, kusarudza zvakakodzera dhigirii yokutsiva uye molecular uremu, etc. Iyo chaiyo nzira inofanira kusarudzwa inoenderana nekushandiswa chaiko. mamiriro uye maitiro ezvinodiwa. Mukushanda chaiko, kazhinji zvinodikanwa kunyatso funga zvinhu zvakawanda uye kugadzirisa zvine musoro uye optimizations kuti ive nechokwadi chekushanda kwakanyanya kweHPMC mhinduro mune chaiyo maapplication.
Nguva yekutumira: Oct-16-2024