Hydroxypropyl methylcellulose (HPMC) ipolymer inoshanda zvakasiyana-siyana ine zvese zviri zviviri hydrophobic uye hydrophilic zvivakwa, zvichiita kuti ive yakasarudzika mumhando dzakasiyana dzekushandisa mumaindasitiri akasiyana.Kuti tinzwisise hydrophobicity uye hydrophilicity yeHPMC, isu tinofanirwa kudzidza chimiro chayo, zvivakwa uye mashandisiro akadzama.
Chimiro che hydroxypropyl methylcellulose:
HPMC inotorwa kubva kune cellulose, yakasikwa polymer inowanikwa muchirimwa sero madziro.Kugadziriswa kwe cellulose kunosanganisira kuunzwa kwehydroxypropyl uye methyl mapoka mu cellulose musana.Iyi shanduko inoshandura zvimiro zvepolymer, ichipa chaiwo zvivakwa zvinobatsira kune akasiyana siyana ekushandisa.
Hydrophilicity yeHPMC:
Hydroxy:
HPMC ine hydroxypropyl mapoka uye iri hydrophilic.Aya mapoka ehydroxyl ane hukama hwepamusoro hwemamorekuru emvura nekuda kwehydrogen bonding.
Hydroxypropyl boka rinogona kuumba hydrogen zvisungo nemamorekuru emvura, zvichiita kuti HPMC inyungudike mumvura kune imwe nhanho.
methyl:
Nepo boka remethyl richibatsira kune yakazara hydrophobicity yemorekuru, haipokane neiyo hydrophilicity yeboka rehydroxypropyl.
Iro methyl boka rinenge risiri-polar, asi kuvapo kweboka re hydroxypropyl kunosarudza hydrophilic character.
Hydrophobicity yeHPMC:
methyl:
Iwo methyl mapoka muHPMC anoona kune imwe nhanho iyo hydrophobicity.
Kunyangwe isiri sehydrophobic semamwe akazara mapolymers, kuvepo kwemapoka emethyl kunoderedza iyo yakazara hydrophilicity yeHPMC.
Mafirimu ekugadzira zvinhu:
HPMC inozivikanwa nekuda kwekugadzira firimu uye inowanzo shandiswa mumishonga uye zvizorwa.Hydrophobicity inobatsira pakuumbwa kwefirimu inodzivirira.
Kudyidzana nezvinhu zvisiri polar:
Mune mamwe maapplication, HPMC inogona kudyidzana neasiri-polar zvinhu nekuda kwechidimbu hydrophobicity.Ichi chivakwa chakakosha kune masisitimu ekuendesa zvinodhaka muindasitiri yemishonga.
Zvikumbiro zveHPMC:
mushonga:
HPMC inoshandiswa zvakanyanya mukugadzirwa kwemishonga sebhainda, firimu rekare, uye viscosity modifier.Kugona kwayo kugadzira firimu kunofambisa kuburitswa kwezvinodhaka.
Inoshandiswa mumuromo yakasimba dosage mafomu akadai semapiritsi uye capsules.
Indasitiri yekuvaka:
Muchikamu chekuvaka, HPMC inoshandiswa mune zvigadzirwa-simende kuvandudza kushanda, kuchengetedza mvura uye kunamatira.
Hydrophilicity inobatsira kuchengetedza mvura, nepo hydrophobicity inobatsira kuvandudza kunamatira.
indasitiri yezvekudya:
HPMC inoshandiswa seyakakora uye gelling mumiriri muindasitiri yechikafu.Yayo hydrophilic chimiro inobatsira kuumba yakagadzikana gels uye kudzora viscosity yezvigadzirwa zvekudya.
cosmetic:
Mukugadzira zvizorwa, HPMC inoshandiswa muzvigadzirwa zvakaita semafuta uye lotions nekuda kweiyo firimu-kugadzira uye kukora zvivakwa.
Hydrophilicity inovimbisa kunaka hydration yeganda.
mukupedzisa:
HPMC ipolymer iyo iri zvese hydrophilic uye hydrophobic.Chiyero chiri pakati pehydroxypropyl nemapoka emethyl muchimiro chayo chinochipa chakasiyana-siyana, chichibvumira kuti ive nehuwandu hwekushandisa.Kunzwisisa zvivakwa izvi kwakakosha pakugadzirisa HPMC kune chaiyo mashandisirwo mumaindasitiri akasiyana, uko kugona kweHPMC kudyidzana nemvura uye nonpolar zvinhu kunoshandiswa kune zvakasiyana siyana.
Nguva yekutumira: Zvita-15-2023