Hydroxypropylmethylcellose (HPMC) uye CarboxyMethylsellose (CMC) marudzi maviri akasiyana ePolymers anoshandiswa mukudonha kweziso, anowanzoshandiswa kudzikisira zviratidzo zveziso. Kunyangwe vachigoverana zvakafanana, aya makomputa aya ane mutsauko wakajeka mumamiriro avo emakemikari, zvivakwa, michina yechiito, uye zvipindinhi zvekiriniki.
Hydroxyprusyl methylcellose (HPMC) ziso rinodonha:
1.comemical chimiro:
HPMC iri synthetic inobva cellulose, polymer yakasikwa inowanikwa mumasango masero emadziro.
Hydroxyprospropyl uye methyl mapoka anounzwa muCellulose chimiro, achipa HPMC yakasarudzika nzvimbo.
2. Viscosity uye rheology:
HPMC ziso remadonhwe kazhinji ane yakakwira viscosity kupfuura zvimwe zvakawanda zvinodonhedza ziso.
Kuwedzera kwescosity kunobatsira madonhwe anoramba ari pane ocular nzvimbo kwenguva yakareba, achirove zororo refu.
3. Mechanism yekuita:
HPMC inoumba inodzivirira uye yakajeka layer pane ocular pamusoro, kuderedza kupokana uye kugadzirisa misodzi yekufambisa yemafirimu.
Iyo inobatsira kudzoreredza kuomesa zviratidzo zveziso nekudzivirira kunyanyisa kwemisodzi.
4. Clinical application:
HPMC ziso remadonhwe rinowanzo shandiswa kurapa rakaoma ziso ziso syndrome.
Ivo zvakare vanoshandiswawo mumahwindo eOPHTRIMIC uye kuvhiya kuti varambe vachiramba hydration.
5 Zvakanakisa:
Nekuda kweiyo yepamusoro viscosity, inogona kuwedzera nguva yekugara pane ocular pamusoro.
Zvinobudirira zvinosunungura zviratidzo zveziso zvakanaka uye zvinopa nyaradzo.
6. Zvakaipa:
Vamwe vanhu vanogona kuona pachena chiratidzo nekukurumidza mushure mekusimbisa nekuda kwekuwedzera kweviscosity.
CarboxyMethylcellose (CMC) ziso remaziso:
1.comemical chimiro:
CMC ndeimwe cellulose derivity yakagadziridzwa ne carboxymethyl mapoka mapoka.
Sumo yeCarboxymethyl boka rinosimudzira mvura yemvura, kugadzira cmc poluble yemvura.
2. Viscosity uye rheology:
CMC Ziso Rakadonha kazhinji vane viscosity yepazasi vachienzaniswa neHPMC ziso remadonhwe.
Iyo yezasi yeVicosity inobvumira kuti ive nyore kushambadzira uye nekukurumidza kupararira pamusoro peiyo ocular pamusoro.
3. Mechanism yekuita:
CMC inoita seyakavharirwa uye huroctant, kuvandudza misodzi yekufambisa yemafirimu.
Iyo inobatsira kudzoreredza yakaoma ziso zviratidzo nekumisikidza dzidziso yekunyoroveswa pane ziso.
4. Clinical application:
CMC ziso remadonhwe anoshandiswa zvakanyanya kudzikisira zviratidzo zveziso.
Ivo vanowanzokurudzirwa kuti vanhu vaine zvinyoro-nyoro kune mwero yakaoma ziso ziso syndrome.
5 Zvakanakisa:
Nekuda kweiyo yakaderera viscoss, inopararira nekukurumidza uye iri nyore kudonhedza.
Zvinobudirira uye nekurumurazve kuregedza maziso eziso.
6. Zvakaipa:
Kuwedzeredzwa kazhinji kunoshanda kunogona kuitwa kuenzaniswa nekwakakwirira viscosity mafomu.
Dzimwe gadziriro dzinogona kunge dzine nguva pfupi yekuita pane ocular pamusoro.
Kufananidza kuongorora:
1. Viscosity:
Hpmc ine yakakwirira viscoss, ichivapa zororo refu-rinogara uye dziviriro yakanyanya kusimba.
CMC ine vhiza yepazasi, kubvumira kukurumidza kupararira uye kupfuurika kushambadzira.
2. Chiitiko Chiitiko:
HPMC inowanzo kupa nguva refu yekuita nekuda kweiyo yepamusoro yepamusoro.
CMC inogona kuda yakawanda nguva inowanzo doses, kunyanya mune zviitiko zveziso rakaoma kwazvo.
3. Nyaradzo Pfupfenyadzo:
Vamwe vanhu vanogona kuona kuti HPMC ziso remadonhwe pakutanga rinokonzeresa kupaza kwenguva pfupi kwechiono nekuda kwekuvonekwa kwavo kwepamusoro.
CMC ziso remadonhwe kazhinji rinotsanangurwa zvakanaka uye kukonzera kushoma kwekutanga blurring.
4. Zviratidzo zveClinical:
HPMC inowanzo kurudzirwa kuvanhu vane mwero kusvika kune yakanyanya kuoma ziso ziso.
CMC inowanzo shandiswa kune nyoro kune mwero mwero maziso uye kune avo vanosarudza mashoma viscous formula.
Hydroxypropylmethylcellose (HPMC) uye CarboxyMethylsellose (CMC) ziso remaziso ndizvo zvese zvakakosha sarudzo dzekurapa maziso akaomeswa eziso. Sarudzo pakati pezviviri zvinoenderana nezvinodiwa nemurwere, kuomarara kweziso rakaoma, uye nguva yaunoda yekuita. HpMC's yakakwira viscosity inopa kudzivirirwa kwenguva refu, nepo maCMC's viscosity inopa zororo nekukurumidza uye inogona kunge iri sarudzo yekutanga kune vanhu vane hanya nekuona kwakashata. VaPolthalmologists uye varapi vechiremba vanowanzo funga izvi zvinhu pavanenge vachisarudza yakakwana yeziso yeziso inodonha yevarwere vavo, yakagadzirirwa kurongedza nyaradzo uye nekubiridzira zvinyoronyoro zviratidzo.
Kutumira Nguva: Dec-25-2023