Hydroxypropyl Methyl Cellulose (HPMC), inozivikanwawo nezita rekutengeserana rekuti hypromellose, ipolymer yakagadzirwa kubva kune yakasikwa cellulose. Iyo yekutanga sosi ye cellulose yekugadzirwa kweHPMC inowanzove yehuni pulp kana donje. Maitiro ekugadzira anosanganisira kugadzirisa kemikari selulosi kuburikidza ne etherification, kuunza hydroxypropyl uye methyl mapoka pane cellulose musana.

Kugadzirwa kweHPMC kunosanganisira matanho akati wandei:

1. Kubvisa Cellulose:
   • Iyo cellulose inowanikwa kubva kune zvidyarwa, kunyanya huni pulp kana donje. Iyo cellulose inobviswa uye inonatswa kuti igadzire cellulose pulp.
2. Alkalization:
   • Iyo cellulose pulp inobatwa nemhinduro yealkaline, kazhinji sodium hydroxide (NaOH), kumisa mapoka ehydroxyl pacheni ye cellulose.
3. Etherification:
   • Etherification ndiyo danho rakakosha mukugadzirwa kweHPMC. Iyo alkalized cellulose inobatwa nepropylene oxide (yemapoka ehydroxypropyl) uye methyl chloride (yemapoka emethyl) kuunza aya mapoka eether pamusana we cellulose.
4. Neutralization uye Washing:
   • Iyo inoguma yakagadziridzwa cellulose, iyo ikozvino Hydroxypropyl Methyl Cellulose, inopinda maitiro e neutralization kubvisa chero asara alkali. Inobva yanyatsosukwa kubvisa tsvina uye ne-products.
5. Kuomesa uye Kugaya:
   • Iyo yakagadziridzwa cellulose yakaomeswa kuti ibvise hunyoro hwakawandisa uye yobva yagayiwa kuita hupfu hwakatsetseka. Iyo particle size inogona kudzorwa zvichienderana neyakagadzirirwa application.

Chigadzirwa cheHPMC chinobva chena kana kuti-chena-chena ine madhigirii akasiyana ehydroxypropyl uye methyl substitution. Iwo chaiwo zvimiro zveHPMC, sekunyungudika kwayo, viscosity, uye humwe hunhu hwekuita, zvinoenderana nedhigirii rekutsiva uye maitiro ekugadzira.

Izvo zvakakosha kuti uzive kuti HPMC ndeye semi-synthetic polymer, uye nepo ichitorwa kubva kune yakasikwa cellulose, inosangana neakakosha makemikari magadzirirwo panguva yekugadzira maitiro kuti iwane yainoda zvivakwa zveakasiyana maindasitiri ekushandisa.