Pharmaceutical Excipient
Hydroxypropyl methylcellulose (HPMC) ichena kana mukaka chena, haina kunhuwa, isinganakidze, fibrous powder kana granule, kuomerwa nekuomeswa hakupfuuri 10%, inonyungudika mumvura inotonhora asi kwete mvura inopisa, zvishoma nezvishoma mumvura inopisa Kuzvimba, peptization, uye kugadzira a viscous colloidal solution, inova mhinduro kana yatonhorera, uye inova gel kana inopisa. HPMC hainyungudike mu ethanol, chloroform uye ether. Inonyungudika mune yakasanganiswa solvent ye methanol uye methyl chloride. Iyo zvakare inonyungudika mune yakasanganiswa solvent yeacetone, methyl chloride uye isopropanol uye mamwe organic solvents. Mushonga waro wemvura unogona kushivirira munyu (mushonga wayo wecolloidal hauparadzwe nemunyu), uye pH ye1% yemvura inogadziriswa ndeye 6-8. The molecular formula of HPMC is C8H15O8-( C10H18O6) -C815O, uye hama molecular mass inenge 86,000.
HPMC ine yakanakisa solubility yemvura mumvura inotonhora. Inogona kunyungudutswa mumhinduro yakajeka nechinguva chiduku mumvura inotonhora. Pane kudaro, haina kunyungudika mumvura inopisa pamusoro pe60 ℃ uye inogona kungozvimba. Iyo isiri-ionic cellulose ether. Mhinduro yaro haina ionic charge, haina kupindirana nesimbi yemunyu kana ionic organic compounds, uye haina kuita nezvimwe zvinhu zvakasvibirira panguva yekugadzirira; ine simba rinopesana ne-allergic properties, uye nekuwedzera kwehuwandu hwekutsiviwa muhutano hwema molecular, iyo Inonyanya kupikisa kune allergies uye yakagadzikana; iyo zvakare ine metabolically inert. Semushonga wemishonga, hauna kugadzirwa kana kunyudzwa. Naizvozvo, haina kupa macalorie mumishonga uye chikafu. Iyo yakaderera calorie, isina munyu, uye isina munyu-isina kuvarwere vane chirwere cheshuga. Mishonga yeAllergenic uye zvokudya zvine kushandiswa kwakasiyana; inenge yakagadzikana kune acids uye alkalis, asi kana PH inokosha inopfuura 2 ~ 11 uye inobatwa nepamusoro pekushisa kana kuti ine nguva yakareba yekuchengetedza, viscosity yayo ichaderera; mhinduro yayo ine aqueous inogona kupa Surface chiitiko, ichiratidza zviri pakati nepakati tension uye interfacial tension; ine emulsification inoshanda mune maviri-phase system, inogona kushandiswa seyakasimba stabilizer uye inodzivirira colloid; mhinduro yayo ine aqueous ine yakanakisa firimu-inogadzira zvimiro, iri piritsi uye piritsi Chinhu chakanaka chekupfeka. Iyo firimu yekuputira yakaumbwa nayo ine zvakanakira kusava neruvara uye kuoma. Kuwedzera glycerin kunogonawo kuvandudza plastiki yayo.
QualiCell HPMC zvigadzirwa zvinogona kuvandudza neinotevera zvivakwa muPharmaceutical Excipient:
·Kana yanyungudika mumvura uye yanyungudutswa kuburikidza nekunyungudutsa, HPMC inogadzira bhaisikopo rakajeka rine simba rakanyanya kusimba.
·Inowedzera simba rekusunga .
·Hydrophilic matrix inoshandiswa pamwe chete neHPMC hydrates kugadzira gel layer, inodzora kuburitsa zvinodhaka.
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