Hydroxypropyl methylcellulose (HPMC) inonzi multifunctional polymer ine mashandisirwo akafara mumaindasitiri akasiyana-siyana akadai semishonga, kuvaka, chikafu, zvizorwa, etc. Izvo zvakasiyana siyana uye mashandiro ayo anoita kuti ive chinhu chakakosha muzvigadzirwa zvakawanda.Heino kuongorora kwakadzama kweHPMC:
1. Hunhu hweHPMC:
Chemical Structure: HPMC inotorwa kubva ku cellulose, yakasikwa polymer inowanikwa muzvirimwa.Inogadzirwa nekemikari inoshandura cellulose ine propylene oxide uye methyl chloride.Iyo dhigirii yekutsiva yehydroxypropyl uye methoxy mapoka inosarudza zvimiro zvayo.
Solubility: HPMC inonyungudika mumvura pane yakakura tembiricha renji.Solubility inoenderana nehuwandu hwekutsiva uye huremu hwemamorekuru epolymer.Kukwirira kutsiva kwemazinga kunounza kuwedzera kunyungudika kwemvura.
Viscosity: HPMC inoratidza pseudoplastic kana shear-kutetepa maitiro, zvichireva kuti viscosity yayo inodzikira pasi pekunetseka kweshear.Iyo viscosity yeHPMC mhinduro inogona kugadziridzwa nekugadzirisa maparamendi akadai semamorekuru uremu, dhigirii rekutsiva, uye kutarisisa.
Kugadzira Firimu: HPMC inoumba akajeka uye anochinjika mafirimu kana akakandwa kubva mumhinduro.Firimu zvimiro zvinogona kugadziridzwa nekugadzirisa polymer concentration uye kuvapo kweplasticizers.
Kugadzikana kwekupisa: HPMC ine kugadzikana kwakanaka kwekupisa, nekuora tembiricha kazhinji iri pamusoro pe200 ° C.Izvi zvinoita kuti ive yakakodzera kune dzakasiyana nzira dzekugadzirisa, kusanganisira inopisa melt extrusion uye jekiseni kuumba.
Hydrophilicity: Nekuda kweiyo hydrophilic hunhu, HPMC inogona kutora uye kuchengetedza yakawanda yemvura.Ichi chivakwa chinobatsira mumashandisirwo akadai seanodzorwa-kuburitsa zvinodhaka kuendesa uye seanokora mumiriri mumasisitimu ane aqueous.
Kugarisana: HPMC inowirirana nezvimwe zvakasiyana-siyana zvezvimwe zvinhu, zvinosanganisira mamwe mapolymers, plasticizers, uye inoshanda mishonga yemishonga (APIs).Uku kugarisana kunobvumira masisitimu akaomarara kuti agadziriswe ane akajairwa maficha.
Non-ionic Properties: HPMC isiri-ionic polymer, zvinoreva kuti haina kutakura chero magetsi.Ichi chivakwa chinoderedza kudyidzana nemhando dzakapomerwa mukugadzira uye inosimudzira kugadzikana kwayo mumhinduro.
2.HPMC mabasa:
Binders: Mukugadzira mapiritsi, HPMC inoshanda sebhainda, ichikurudzira kunamatira pakati pezvikamu uye kuwedzera simba remagetsi repiritsi.Inobatsirawo mahwendefa kuparara mushure mekudya.
Firimu Coating: HPMC inoshandiswa zvakanyanya semugadziri wekuvhara firimu yemapiritsi nemakapisi.Inoumba yunifomu, inodzivirira iyo inovhara kuravira uye kunhuwa kwemushonga, inowedzera kugadzikana, uye inobatsira kumedza.
Kusunungurwa kwakasimudzirwa: HPMC inogona kushandiswa kudzora kuburitswa kwemishonga kubva kumafomu emushonga.Nekunyorovesa kuti igadzire gel layer, HPMC inogona kunonoka kuburitswa kwezvinodhaka uye kupa mhedzisiro yekurapa.
Viscosity Modifier: Mune aqueous masisitimu, HPMC inoita senge viscosity modifier kana thickener.Inopa pseudoplastic kuyerera maitiro, inovandudza kugadzikana uye kushanda kwekushandisa kwemaitiro akadai semafuta, lotions uye gels.
Suspending agent: HPMC inoshandiswa kudzikamisa kumiswa kwezvisinganyunguriki zvimedu mukuumbwa kwemvura.Inodzivirira kugadzirisa nekuwedzera viscosity yechikamu chinoenderera uye kuwedzera particle dispersion.
Emulsifier: Mukugadzira emulsion, HPMC inodzikamisa iyo interface pakati pemafuta nemvura zvikamu, kudzivirira kupatsanurwa kwechikamu uye emulsification.Inovandudza kugadzikana uye hupenyu hwesherufu hwemafuta muzvigadzirwa zvakadai semafuta, mafuta uye mafuta.
Kuumbwa kweHydrogel: HPMC inogona kuumba mahydrogel kana yaiswa mvura, ichiita kuti ishande mumaronda ekupfeka, malenzi ekuonana, uye masisitimu ekuendesa zvinodhaka.Aya ma hydrogel anopa nharaunda yakanyorova yekupora maronda uye anogona kutakurwa nemishonga yekuendesa yemuno.
Thickening Agent: HPMC inowanzoshandiswa seyakakora muzvigadzirwa zvekudya senge sosi, madhirezi uye madhiri.Inopa hunyoro hwakatsetseka uye inosimudzira kuravira pasina kushandura flavour kana zvinovaka muviri.
Kuvaka Kuwedzera: Muindasitiri yekuvaka, HPMC inoshandiswa sechinhu chinochengeta mvura mumasimende-based mortars uye plasters.Inovandudza kushanda, kunamatira, uye inoderedza kutsemuka nekunonoka kubuda kwemvura.
Surface Modhifita: HPMC inogona kushandura iyo yepamusoro zvimiro zveakasimba substrates senge bepa, machira uye ceramics.Inovandudza kudhindwa, kunamatira uye zvipingamupinyi zvezvipfeko nemafirimu.
Hydroxypropylmethylcellulose (HPMC) i polymer inoshanda zvakasiyana-siyana ine zvakasiyana-siyana zvezvivakwa uye mabasa.Solubility yayo, viscosity, kugona kugadzira firimu uye kuenderana kunoita kuti ive chinhu chakakosha mukushandisa kwakawanda mumaindasitiri.Kubva kumishonga kusvika pakuvaka, chikafu kusvika kune zvekuzora, HPMC inoramba ichiita basa rakakosha mukuvandudza kuita kwechigadzirwa uye kunaka.Sezvo kutsvagisa uye tekinoroji inofambira mberi, kuita kwakasiyana-siyana uye kushandiswa kweHPMC kunogona kuwedzera kuwedzera, kutyaira hunyanzvi mukugadzira dhizaini uye kugadzirwa kwechigadzirwa.
Nguva yekutumira: Feb-23-2024