Muminda yesainzi yezvigadzirwa uye kuvaka, zvekuwedzera zvinotora basa rakakosha mukusimudzira akasiyana siyana emidziyo.Hydroxypropyl methylcellulose (HPMC) chimwe chekuwedzera chakagamuchira tarisiro huru yekugona kwayo kuvandudza zvinhu zvekunamira mumhando dzakasiyana dzekushandisa.
Zviwedzerwa chikamu chakakosha chemunda wesainzi yemidziyo uye chinowanzoshandiswa kusimudzira zvimiro zvezvinhu zvakasiyana.Pakati peizvi zvinowedzera, hydroxypropyl methylcellulose (HPMC) yave mutambi akakosha, kunyanya mukuvandudza zvinhu zvekunamatira.Adhesive zvivakwa zvakakosha mumaindasitiri akawanda, anosanganisira kuvaka, mishonga uye chikafu, uko kusimba uye kusimba kwechisungo kunokanganisa zvakanyanya kushanda uye hupenyu hurefu hwechigadzirwa.
1. Nzwisisa Hydroxypropyl Methylcellulose (HPMC)
Hydroxypropyl methylcellulose (HPMC) inotorwa kubva ku cellulose uye inoshandiswa zvakanyanya mumaindasitiri akasiyana nekuda kwemabasa ayo akawanda.Inogadzirwa kuburikidza nekugadziriswa kwemakemikari ye cellulose, umo hydroxypropyl uye methyl mapoka anounzwa mu cellulose musana.Kugadziridzwa uku kunopa musanganiswa wakasarudzika zvimiro, zvinosanganisira yakakwira kunyungudika kwemvura, kugona kugadzira firimu, uye zvakanyanya kukosha, kugona kusimudzira zvinhu zvinonamira.
2.Iyo nzira iyo HPMC inovandudza adhesive properties
Kugona kweHPMC kukwidziridza zvimiro zvekunamira kunobva muchimiro chayo chemorekuru uye kudyidzana nezvimwe zvinhu.Kana yakanyungudutswa mumvura, iyo HPMC mamorekuru hydrate, ichigadzira viscous mhinduro.Mushonga wacho unoshanda sebhainda, uchikurudzira kuumbwa kwezvisungo zvakasimba pakati pezvikamu kana nzvimbo.Pamusoro pezvo, mamorekuru eHPMC ane mapoka anoshanda anogona kudyidzana neiyo substrate pamusoro, achisimudzira kunamatira uye kubatana.Kudyidzana uku kunobatsira kuvandudza kunyorova, kupararira uye kubatana kwemukati, izvo zvinhu zvakakosha pakuwana zvisungo zvakasimba uye zvinogara kwenguva refu.
3. Kushandiswa kweHPMC mumaindasitiri akasiyana-siyana
Iko kuita kwakasiyana-siyana kweHPMC kunoita kuti ive yakakosha zvakanyanya kune akasiyana maindasitiri.Muchikamu chekuvaka, HPMC inowanzo shandiswa sekuwedzera kune simende-yakavakirwa zvinhu zvakaita sedhaka nekongiri.Nekuvandudza chisungo pakati pemasimende uye aggregate, HPMC inowedzera simba, kushanda uye kusimba kwezvinhu izvi.Saizvozvo, muindasitiri yemishonga, HPMC inoshandiswa mukuumbwa kwepiritsi kuti ivandudze kubatana kwehupfu uye kuve nechokwadi chekuburitswa kwezvinodhaka yunifomu.Pamusoro pezvo, muindasitiri yechikafu, HPMC inoshandiswa seyakagadzikana uye yakakora, ichibatsira kuvandudza magadzirirwo uye viscosity yezvikafu vachiwedzera hupenyu hwavo hwesherufu.
4. Nyaya Yekudzidza: Kushanda Kushandiswa kweHPMC
Kuenderera mberi nekuratidza kushanda kweHPMC mukuvandudza zvivakwa zvekubatanidza, akati wandei zvidzidzo zvinogona kuongororwa.Muindasitiri yekuvaka, chidzidzo chekushandiswa kweHPMC mumadhaka ekuzvimisa-leveling yakaratidza kuwedzera kukuru kwesimba rebhondi uye kuramba kutsemuka.Saizvozvo, mukugadzirwa kwemishonga, zvidzidzo zvakaratidza kuti mahwendefa ane HPMC anoratidza epamusoro mechanical zvivakwa uye dissolution profiles zvichienzaniswa nemapiritsi asina HPMC.Izvi zvidzidzo zvenyaya zvinoratidzira kubatsira kweHPMC mumashandisirwo epasirese, ichisimbisa kushanda kwayo mukusimudzira zvivakwa zvekubatanidza mumaindasitiri akasiyana.
5. Tariro nezvinetso zveramangwana
Kuenderera mberi, kushandiswa kwezvinowedzera zvakaita seHPMC kusimudzira zvivakwa zvekubatanidza zvinovimbisa kuenderera mberi nekukura.Kufambira mberi kwesainzi yezvekushandisa uye engineering yemakemikari inogona kutungamira mukuvandudzwa kwezvinowedzera zvinowedzera nekuita kwakakura uye kuita kwakasiyana-siyana.Nekudaro, matambudziko akadai sekudhura-kushanda, kusimbaradza kwezvakatipoteredza uye kuteedzera kwemitemo kunofanirwa kutariswa kuti ive nechokwadi chekugamuchirwa kwakapararira kweizvi zvinowedzera.Pamusoro pezvo, kumwe kutsvagurudza kunodiwa kuti unzwisise zvizere maitiro echiito uye kugadzirisa magadzirirwo nekushandiswa kweHPMC-yakavakirwa zvigadzirwa.
Zvinowedzerwa senge hydroxypropyl methylcellulose (HPMC) inoita basa rakakosha mukuvandudza kunamatira.Ding Property inotora mafambiro ese ehupenyu.Kuburikidza neyakasarudzika mamorekuru chimiro uye kudyidzana, HPMC inosimudzira kunamatira, kubatana uye kubatana kwemukati, nekudaro ichisimbisa chisungo pakati pezvimedu kana nzvimbo.Kushanda kwakasiyana-siyana uye kushanda kwayo kunoita kuti ive yakakosha mumashandisirwo akadai sekuvaka, mishonga uye chikafu.Sezvo tsvakiridzo nebudiriro zvichiramba zvichifambira mberi, ramangwana rinopa mikana yakakura yekuwedzera nekushandisa HPMC uye zvimwewo zvekuwedzera kuti uwedzere kuita kwekubatana uye kutyaira hunyanzvi uye kusimba muinjiniya yezvinhu.
Nguva yekutumira: Feb-28-2024