Hydroxypropylmethylcellulose (HPMC) isanganiswa uye inoshanda zvakasiyana-siyana ndeyemhuri ye cellulose ether.Inotorwa kubva ku cellulose, yakasikwa polymer inowanikwa mumiti yesero madziro.HPMC inoshandiswa zvakanyanya mumaindasitiri akasiyana anosanganisira emishonga, chikafu, kuvaka uye zvekuzora nekuda kwezvakasiyana zvivakwa uye akawanda mabhenefiti.
1. Indasitiri yemishonga:
A. Sustained kusunungurwa gadziriro:
HPMC inoshandiswa zvakanyanya muindasitiri yemishonga nekuda kwekugona kwayo kuumba gel matrix kana hydrated.Ichi chivakwa chinonyanya kubatsira mukuvandudza-inoburitswa-yakaburitswa mishonga yekugadzira.Nekudzora viscosity uye gelation rate yeHPMC, vagadziri vemishonga vanogona kuwana akawedzera kuburitswa kwemishonga profiles, kuvandudza kutevedza kwevarwere uye kuderedza dosing frequency.
b.Mucheka wefirimu wakaonda:
HPMC inowanzoshandiswa semugadziri wekuvhara firimu pamapiritsi.Inopa jira rakatsetseka, rakafanana rinowedzera kutaridzika kwemapiritsi, rinovhara kuravira kwemushonga, uye rinodzivirira kubva kune zvakatipoteredza.Iyo firimu-kugadzira zvimiro zveHPMC zvinobatsira kuvandudza kugadzikana kwezvinodhaka uye bioavailability.
C. Kutengeswa Kwezvinodhaka:
Iyo biocompatibility uye inert chimiro cheHPMC chinoita kuti ive yakakodzera kushandiswa mune inodzorwa dhizaini masisitimu.Inogona kushandiswa pamwe chete nemamwe mapolymers kuenzanisa kinetics yekuburitsa zvinodhaka, ichibvumira kutonga chaiko kwemitengo yekuunza zvinodhaka uye kuderedza njodzi yemhedzisiro.
d.Tablet binder:
HPMC inoshanda sebhainda repiritsi rinoshanda, richibatsira kupa kunamira kune kugadzirwa kwehwendefa.Inovimbisa kusungirirwa kwakakodzera kwezvinhu, zvichiita kuti yunifomu yakaoma uye kuvimbika kwemapiritsi.
2. Indasitiri yezvekudya:
A. Thickeners uye gelling agents:
Muindasitiri yechikafu, HPMC inoshandiswa seyakakora uye gelling agent.Inopa chikafu chimiro chinodiwa uye inovandudza hutano hwayo hwose.HPMC inowanzo shandiswa muzvigadzirwa zvakaita sesoso, soups uye madheti kuti uwane kuenderana kwaunoda.
b.Kutsiva mafuta:
HPMC inogona kushandiswa sechinotsiva mafuta mune zvimwe zvekudya, zvichibatsira kugadzira yakaderera-mafuta kana mafuta-isina dzimwe nzira.Izvi zvinonyanya kukosha mumamiriro ekugadzirisa nyaya dzehutano dzine chokuita nemafuta akawandisa.
C. emulsification:
Nekuda kweiyo emulsifying zvivakwa, HPMC inoshandiswa mukugadzira emulsified chikafu.Inobatsira kudzikamisa emulsions, kudzivirira kuparadzaniswa kwechikamu uye kuve nechokwadi chehomogeneous chigadzirwa.
d.Polishing agent:
HPMC inoshandiswa sechinhu chinopenya muindasitiri yechikafu kuti ipe inopenya uye inotaridzika inoyevedza coating kumaswiti, michero uye zvimwe zvigadzirwa zvekudya.
3. Indasitiri yekuvaka:
A. Matairi anonamira:
HPMC chinhu chakakosha muzvigadzirwa zvematairi uye inoshanda seyakakora uye inochengetedza mvura.Inosimudzira kushanda kwedhaka rekubatanidza, kuita kuti kuvaka kuve nyore uye kunatsiridza kusimba kwechisungo.
b.Simende dhaka:
Mumasimende-based mortars, HPMC inoshandiswa kuvandudza kuchengetedza kwemvura, kushanda uye kunamatira.Inobatsira kuvandudza zvinhu zvose zvedhaka, zvichiita kuti zvive nyore kubata uye kuve nechokwadi chekunamatira zviri nani pamusoro.
C. Makomisheni ekuzvienzanisa:
HPMC inosanganisirwa mumakomisheni ega-leveling kudzora viscosity uye kunatsiridza kuyerera maitiro.Izvi zvakakosha kuti uwane nzvimbo yakatsetseka, nhanho paunenge uchiisa pauriri.
d.Gypsum uye stucco:
Kuwedzera HPMC kune gypsum uye stucco maumbirwo anovandudza kunamatira, kushanda uye kuchengetedza mvura.Inobatsira kuvandudza hutano hwese hwepamusoro hwakapedzwa, kuderedza mukana wekutsemuka uye kuwedzera kusimba.
4. Indasitiri yezvizoro:
A. Thickeners mumakirimu uye lotions:
HPMC inowanzoshandiswa seyakakora mumiriri mune zvizorwa maumbirwo akadai makirimu uye lotions.Inopa chigadzirwa chimiro chakatsetseka, chine cream uye chinosimudzira hunhu hwayo hwekunzwa.
b.Mafirimu ekugadzira maajenti mune zvigadzirwa zvekuchengeta bvudzi:
Muzvigadzirwa zvekuchengetedza bvudzi senge gel dzebvudzi uye styling creams, HPMC inoshanda semugadziri wekugadzira firimu.Inobatsira kuumba firimu rinoshanduka, rinogara riri pabvudzi, rinobatsira kuvandudza kubata nekugadzirisa.
C. Emulsion stabilizer:
Iyo inodzikamisa zvimiro zveHPMC inoita kuti ive yakakosha mukuumbwa kweemulsion kudzivirira kuparadzaniswa kwechikamu uye kuve nechokwadi chekugadzikana kwechigadzirwa nekufamba kwenguva.
d.Kuburitswa kwakadzorwa muzvinyorwa zvemusoro:
Zvakafanana nekushandiswa kwayo mumishonga, HPMC inogona kushandiswa mukugadzira zvizorwa kuti iwane inodzorwa kuburitswa kwezvinhu zvinoshanda.Izvi zvinonyanya kukosha kune zvigadzirwa zvekuchengetedza ganda zvinoda kuburitswa kwakasimba kwemakomisheni anobatsira.
5. Zvimwe zvakanakira:
A. Kuchengeta mvura:
HPMC ine yakanakisa yekuchengetedza mvura zvivakwa, zvichiita kuti ive yakakosha mumhando dzakasiyana dzekushandisa uko kuchengetedza hunyoro hwakakosha.Izvi zvinonyanya kubatsira mune mamwe magadzirirwo muindasitiri yekuvaka uye mumaindasitiri ezvekudya uye ekuzora.
b.Biodegradability:
HPMC i biodegradable polymer inoenderana nekukura kwekusimbisa kune zvakatipoteredza zvine hushamwari uye zvinogoneka zvinhu.Yayo biodegradable zvimiro zvinoderedza kukanganiswa kwezvakatipoteredza, zvichiita kuti ive sarudzo yekutanga kune mamwe maapplication.
C. Kuenderana nemamwe mapolima:
HPMC ine kugarisana kwakanaka nemamwe akasiyana mapolymers, achibvumira masisitimu akaomarara kuumbwa zvinoenderana nezvinodiwa zvekushandisa.
d.Kwete-chepfu uye inert:
HPMC inoonekwa seisina chepfu uye inert, ichiita kuti ive yakachengeteka kushandiswa mumishonga, chikafu, zvizorwa uye zvimwe zvinoshandiswa uko kuchengetedza kwevatengi kwakakosha.
Hydroxypropyl methylcellulose (HPMC) inomira pachena mumaindasitiri akasiyana-siyana semusanganiswa uye unobatsira.Inobatsira kugadzira masisitimu anodzorwa-kuburitswa, kuwedzera mashandiro echikafu uye zvizorwa, uye kuvandudza zvimiro zvezvivakwa zvekuvaka, zvichisimbisa kuita kwayo uye kukosha kwayo mumagadzirirwo emazuva ano ekugadzira.Sezvo indasitiri iri kuramba ichishanduka, HPMC inogona kuramba iri chinhu chakakosha mukugadzira zvigadzirwa zvemhando yepamusoro uye zvemhando yepamusoro.
Nguva yekutumira: Zvita-18-2023