Hydroxypropyl methylcellulose (HPMC) coating chinhu chakasiyana-siyana chinoshandiswa zvakanyanya mumhando dzakasiyana dzekushandisa mumaindasitiri akasiyana siyana.HPMC is a semi-synthetic, inert, isiri-chepfu polima inotorwa kubva muselulosi.Inowanzoshandiswa sechinhu chekuputira chemishonga, chikafu uye zvimwe zvigadzirwa.Iyo yakasarudzika zvimiro zveHPMC inoita kuti ive yakanakira kune akasiyana coating application uye mashandisiro ayo apararira.
1. Zvikumbiro zvekurapa:
Tablet film coating:
HPMC inoshandiswa zvakanyanya senge firimu rekuvhara zvinhu zvemapiritsi emishonga.Mabhaisikopu emushonga anopa chidziviriro chinogona kuvhara kuravira, hwema, kana ruvara rwemushonga, zvichiita kuti zvive nyore kuvarwere kuugamuchira.Pamusoro pezvo, inovandudza kugadzikana uye pasherufu yehupenyu hwemishonga, inovadzivirira kubva kune zvakatipoteredza, uye inofambisa inodzorwa-kuburitswa maumbirwo.
Kugadziriswa kwekusunungurwa kwakagadziriswa:
Kudzorwa uye kuenderera kusunungurwa kwezvinodhaka chinhu chakakosha pakugadzirwa kwezvinodhaka.HPMC inowanzoshandiswa kugadzira matrices anopa kwenguva refu inodzorwa kuburitswa kwezvinodhaka.Izvi zvakakosha kune mishonga inoda kwenguva refu yekurapa maitiro.
Enteric coating:
HPMC inoshandiswawo mukugadzira enteric coating formulations kuchengetedza zvinodhaka kubva munzvimbo ine acidic yemudumbu.Izvi zvinobvumira kuti mushonga wacho usunungurwe mumatumbo kuitira kuti ugone kutorwa zvakanyanya.Enteric coatings yakajairika mumishonga inobata gastric acid kana inoda kuburitswa kwakanangwa.
Kuravira masking:
HPMC machira anogona kushandiswa kuvhara kuravira kusingafadzi kweimwe mishonga uye kunatsiridza kuterera kwemurwere.Izvi zvinonyanya kukosha kuvana nevakwegura vane dambudziko rekumedza kana kuti vanonzwa kuravira kwemishonga.
Hunyoro hunodzivirira hunyoro:
HPMC coatings inopa hunyoro chipingamupinyi chinodzivirira zvigadzirwa zvemishonga kubva kunyoro uye nharaunda mwando.Izvi zvakakosha kuchengetedza kugadzikana kwemishonga inonzwa mwando.
2. Chikafu indasitiri yekushandisa:
Zvokudya zvinodyiwa:
Muindasitiri yechikafu, HPMC inoshandiswa sechinhu chinodyiwa pamichero, miriwo uye zvimwe zvigadzirwa zvekudya.Uku kupfekedza kunoshanda sechipingamupinyi pakunyorova uye oksijeni, zvichibatsira kuwedzera hupenyu hwesherufu yezvinhu zvinoparara, nekudaro kuderedza kuparara.
Kugadziriswa kwechimiro:
HPMC inoshandiswa kugadzirisa magadzirirwo emhando dzakasiyana dzezvigadzirwa zvekudya.Inowedzera muromo, inowedzera viscosity uye inodzikamisa emulsions mukugadzirwa kwezvokudya.Izvi zvinonyanya kukosha mukugadzirwa kwemasosi, mapfekero uye zvigadzirwa zvemukaka.
ChiPolish:
HPMC inoshandiswa sechinhu chinopenya chezvihwitsi uye zvihwitsi.Inopa inopenya inodzivirira iyo inonatsiridza kutaridzika uye inowedzera kutsva kwechigadzirwa.
Kutsiva mafuta:
HPMC inogona kushandiswa sechinotsiva mafuta mune yakaderera-mafuta kana mafuta-isina chikafu.Inobatsira kuvandudza magadzirirwo uye muromo wechigadzirwa chako pasina kuwedzera akawanda emafuta macalorie.
3. Kushanda muindasitiri yekuvaka:
Tile adhesive:
HPMC inoshandiswa mumatairi e ceramic adhesives kuvandudza kushanda kwechinhu, kuchengetedza mvura uye kusungirira zvivakwa.Inowedzera kusimba kwechisungo uye inodzivirira kuoma kusati kwasvika kwekunamatira.
Doka uye shanduro:
Muzvivakwa zvekuvaka senge madhaka uye plasters, kuwedzerwa kweHPMC kunovandudza kuwirirana, kushanda uye kuchengetedza mvura.Inoita seyakakora uye inobatsira kuzadzisa zvinodiwa zvechigadzirwa chekupedzisira.
Gypsum-based products:
HPMC inoshandiswa mune gypsum-based zvigadzirwa zvakadai sejoint compound uye stucco kuvandudza kuwirirana uye kuchengetedza mvura.Inobatsira kurerutsa kushandiswa uye kupera kwezvinhu izvi.
4. Zvigadzirwa zvekuchengeta wega:
Zvigadzirwa zvekuchengetedza bvudzi:
HPMC inoshandiswa seyakakora uye inodzikamisa muma shampoos, maconditioner uye zvigadzirwa zvekugadzira bvudzi.Inobatsira kuzadzisa inodiwa manyorerwo, viscosity uye kuita kwese kwezvigadzirwa izvi.
Topical gadziriro:
HPMC iri mumhando dzakasiyana-siyana dzekugadzirira senge makirimu, lotions, uye gels.Inobatsira kuvandudza maitiro, kupararira uye kugadzikana kwezvigadzirwa izvi paganda.
5. Mamwe maapplication:
Indasitiri yemachira:
Muindasitiri yemachira, HPMC inoshandiswa seyakakora mukudhaya uye kudhinda maitiro.Inobatsira kudzora viscosity yemhinduro yedhayi uye inovimbisa kunyange kugovera pamucheka.
Adhesive:
HPMC inoshandiswa mukunamira maumbirwo ekuvandudza chisungo simba, viscosity uye processability.Inonyanya kukosha mumvura-based adhesives.
Pepa coating:
Muindasitiri yemapepa, HPMC inoshandiswa sechinhu chekupotera kuvandudza mapeji epamusoro zvinhu senge kutsvedzerera, kudhinda uye kunamatira inki.
Zvakanakira zveHPMC coating:
Biocompatibility:
HPMC inowanzoonekwa yakachengeteka kudyiwa nevanhu, zvichiita kuti ive yakakodzera kushandiswa mumishonga uye chikafu.Iyo biocompatible uye haikonzeri kukanganisa kwakashata mumuviri.
Mafirimu ekugadzira zvinhu:
HPMC inoumba mafirimu anochinjika uye mayunifomu, zvichiita kuti ive sarudzo yakanaka yekuputira maapplication.Ichi chivakwa chakakosha pamishonga yemafirimu ekuputira uye kuumbwa kwezvikamu zvekudzivirira mumaindasitiri akasiyana.
Zvakasiyana-siyana:
HPMC ine huwandu hwakawanda hwekushandisa, kubva kumishonga kusvika kune chikafu uye zvekuvaka.Kuchinjika kwayo kunobva pakukwanisa kwayo kushandura zvinhu zvakasiyana-siyana senge viscosity, kuumbwa uye kunamatira.
Thermal kugadzikana:
HPMC machira akagadzikana nemafuta, ayo akakosha kune mishonga uye zvimwe zvigadzirwa zvinogona kuoneswa kushanduka kwekushisa panguva yekuchengetedza nekufambisa.
Kuburitswa kunodzorwa:
Kushandiswa kweHPMC mukugadzirwa kwemishonga kunogonesa kudzora uye kuenderera kusunungurwa kwezvinodhaka, zvichibatsira kuvandudza kurapa kwakanaka uye kutevedzera murwere.
Kuchengeta mvura:
Muzvivakwa zvekuvaka, HPMC inosimudzira kuchengetwa kwemvura, inodzivirira kuoma nguva isati yakwana uye inova nechokwadi chekurapa kwakakodzera.Ichi chivakwa chakakosha pakuita kwemateki, anonamira uye machira.
Zvinoenderana nemamiriro ekunze:
HPMC inotorwa kubva kune yakasikwa cellulose masosi uye saka ine hushamwari kwezvakatipoteredza.Iyo ine biodegradable uye haikonzeri zvakanyanya kukuvadza kwezvakatipoteredza.
Kuenderana uye kugadzikana:
HPMC inobatsira kuvandudza kuenderana uye kugadzikana kweakasiyana maumbirwo, kuve nechokwadi kuti zvigadzirwa zvinochengeta zvavanoda kuita nekufamba kwenguva.
mukupedzisa:
Iko kushandiswa kwehydroxypropyl methylcellulose (HPMC) machira akapararira uye akasiyana mumaindasitiri mazhinji.Yayo yakasarudzika zvimiro, senge firimu-kugadzira kugona, biocompatibility uye versatility, inoita kuti ive chinhu chakakosha mumishonga yemishonga, chikafu, kuvaka, kuchengetwa kwemunhu, machira nemimwe minda.Sezvo tekinoroji uye zvinodiwa zveindasitiri zvichiramba zvichishanduka, HPMC inogona kuramba iri mutambi akakosha mukushandisa machira, ichibatsira mukuvandudza nekuvandudza zvigadzirwa munzvimbo dzakasiyana siyana.
Nguva yekutumira: Zvita-14-2023