Hydroxypropyl Methylcellulose (HPMC) ipolymer inoshanda zvakasiyana-siyana inowana mashandisirwo akawandisa mumaindasitiri akasiyana, anosanganisira mishonga, chikafu, kuvaka, uye zvekuzora.
1. Nhanganyaya kuHPMC:
Hydroxypropyl Methylcellulose (HPMC) ndeye semi-synthetic, inert, viscoelastic polymer inotorwa kubva muselulosi.Inogadzirwa kuburikidza nekugadziriswa kwemakemikari ye cellulose, iyo inosanganisira etherification yealkali cellulose ine propylene oxide uye methyl chloride.Chigadzirwa chacho ivhu chena kusvika kuchena, risinganhuhwi, uye risingaravi rinonyungudika mumvura asi risinganyunguriki muzvinonyungudutsa zvinonyungudutsa.
2. Mamiriro neZvinhu:
Chimiro cheHPMC chine musana we cellulose, polima yakasikwa yakagadzirwa nemayuniti eglucose akabatanidzwa ne β(1→4) glycosidic bond.MuHPMC, mamwe emapoka ehydroxyl pazvikamu zveglucose anotsiviwa ne2-hydroxypropyl uye methyl mapoka.Kutsiva uku kunoshandura zvimiro zvepolymer zvichienzaniswa neyemuno selulosi, zvichipa yakagadziridzwa solubility, viscosity, uye kugona kugadzira firimu.
Zvimiro zveHPMC zvinosiyana zvichienderana nezvinhu zvakaita sedhigirii rekutsiva (DS), uremu hwemamorekuru, uye kugovera saizi yechikamu.Kazhinji, HPMC inoratidza:
Zvakanakisa zvekugadzira firimu
Thermal gelation maitiro
Mvura yakakwirira yekuchengetedza simba
Kugadzikana pamusoro pehupamhi pH renji
Kuenderana nemamwe ma polymers uye additives
Non-ionic zvisikwa, zvichiita kuti ienderane nezvinhu zvakasiyana-siyana
3. Synthesis yeHPMC:
Iyo synthesis yeHPMC inosanganisira akati wandei matanho:
Alkali cellulose kugadzirira: Cellulose inorapwa nealkaline solution kugadzira alkali cellulose.
Etherification: Alkali cellulose inopindirana nepropylene oxide uye methyl chloride kuunza hydroxypropyl uye methyl mapoka kumusana we cellulose.
Kugezeswa nekucheneswa: Chigadzirwa chinobuda chinogezwa, chinonatswa, uye chinocheneswa kubvisa tsvina.
Kuomesa: Iyo yakacheneswa HPMC yakaomeswa kuti iwane chigadzirwa chekupedzisira muhupfu.
4. Zvishandiso zveHPMC:
HPMC inowana zvikumbiro zvakapararira mumaindasitiri akasiyana siyana:
Pharmaceuticals: HPMC inoshandiswa zvakanyanya semushonga wemishonga mumapiritsi ekuputira, kudzorwa-kuburitswa kwemaitiro, kugadzirira kwemaziso, uye kumiswa.Iyo inoshanda sebhainda, thickener, firimu rekare, uye inosimudzira-kuburitsa mumiriri mune akasiyana dosage mafomu.
Indasitiri yeChikafu: Muindasitiri yechikafu, HPMC inoshandiswa seyakakora, inodzikamisa, emulsifier, uye mumiriri wekuchengetedza hunyoro mune zvigadzirwa senge zvakabikwa, zvigadzirwa zvemukaka, sosi, uye madhiri.Inovandudza kuumbwa, hupenyu hwesherufu, uye muromo muzvigadzirwa zvekudya.
Kuvaka: HPMC chinhu chakakosha mumidziyo yekuvaka senge simende-based mortars, mataira anonamira, uye gypsum-based zvigadzirwa.Inoshanda semugadziri wekuchengetedza mvura, inovandudza kushanda, inoderedza kusagika, uye inosimudzira kunamatira mukuumbwa kwekuvaka.
Cosmetics: HPMC inoshandiswa muzvizora uye zvigadzirwa zvekuchengeta munhu seanokora, anosimbisa, uye anogadzira firimu muzvigadzirwa zvakaita semafuta, lotions, shampoos, uye gels.Inopa viscosity, inosimudzira kuumbwa, uye inopa yakatsetseka, isina-mafuta kunzwa.
Zvimwe Zvishandiso: HPMC inoshandiswawo mukudhinda machira, ceramics, pendi, detergents, uye semafuta mune akasiyana maindasitiri maitiro.
5. Maonero Nematambudziko Eramangwana:
Iko kudiwa kweHPMC inotarisirwa kuramba ichikura nekuda kwezvivakwa zvayo zvakasiyana-siyana uye kushandiswa kwakasiyana.Nekudaro, zvinonetsa zvakaita sekuchinja-chinja kwemitengo yezvinhu, zvirambidzo, uye kukwikwidza kubva kune mamwe mapolymers zvinogona kukanganisa misika.Kuedza kutsvagisa kwakanangana nekusimudzira mashandiro eHPMC, kuongorora nzira dzakasimba dzekubatanidza, uye kuwedzera mashandisiro ayo mundima dziri kusimukira dzakadai sebiomedicine uye nanotechnology.
Hydroxypropyl Methylcellulose (HPMC) ipolymer yakakosha ine huwandu hwakasiyana hwekushandisa mumaindasitiri akawanda.Chimiro chayo chakasiyana, zvivakwa, uye synthesis inoita kuti ive chinhu chakakosha mumishonga yemishonga, zvigadzirwa zvekudya, zvekuvakisa, zvekuzora, uye akasiyana maindasitiri ekushandisa.Sezvo kutsvagisa nekusimudzira kuri kuenderera mberi, HPMC yakagadzirira kuramba iri mutambi akakosha muindastiri yepolymer, ichipa zvigadziriso zvitsva zvekusangana nezvinoda musika.
Nguva yekutumira: Mar-05-2024